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Gabapentin increases risk of dementia. Instead of just covering up pain, people should seek solutions that address the root cause, a path where regenerative medicine offers a promising alternative.

The evidence for knee "clean ups" (arthroscopic debridements) for degenerative meniscus and osteoarthritis is very poor yet continues to be recommended. Platelet Rich Plasma (PRP) presents an alternative to this route by reducing pain while preserving joint health long term.

A review published this month (May 2025) looks at the effect of PRP on large joint osteoarthritis over time and finds that more is better.

A recently published meta-analysis of the last 60 years of research examines the effectiveness of PRP and cortisone in treating knee osteoarthritis. Unsurprisingly, and in line with the whole of the scientific literature, PRP was shown to be superior to cortisone for knee osteoarthritis pain with less side effects.

The study found that MFAT could provide significant pain relief and improve joint functionality compared to steroids and a saline injection.